Denali Therapeutics is dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and biomarker driven drug development in areas of high unmet medical need.
In anticipation of the Company’s growth plans, Denali Therapeutics is seeking to recruit an Associate Director, Medical Affairs. Reporting to the Director of Medical Affairs, the incumbent will be responsible for input into developing medical strategy and tactical execution for molecule projects, fostering partnerships and collaborations within the scientific community, supporting ongoing development clinical trial efforts, and contributing to medical input on projects and teams.
This is a unique opportunity to contribute scientifically toward Denali’s mission to defeat degeneration and simultaneously help establish the infrastructure and culture of a growing medical affairs organization.
Communications/Publications: Drive external communications strategy and pull through publications strategy and execution, including maximizing program representation at scientific congress
Clinical Trial Support: Build awareness and excitement of clinical trial programs to support rapid trial enrollment
CDP Evolution: Ensure external insights are gathered, distilled, and incorporated into evolving clinical development plans
Medical Content: Develop strategic and insight driven medical content across multiple stakeholders including scientific narrative and lexicon for key data sets, e.g., unmet need, biomarkers, safety, efficacy
Medical Strategy: Develop and drive program specific medical affairs strategy for DNL310 and DNL343
Medical Planning: Design and execute gap-identified data generation including trials (3b/IV), real-world data, etc. toward launch
Vendor outsourcing, oversight, and management
Collaboratively participate and provide input on cross-functional teams and projects with the ability to influence across the organization
Represent Denali’s values, rigor, and excellence both internally and externally
Act as a champion for high standards of compliance, ethics, and safety, always putting patients first
Advanced degree (PhD, PharmD or equivalent ex-US degree); experience in rare disease and/or neuroscience strongly preferred
2-5+ years of biotechnology or pharmaceutical medical affairs and 2+ years in leadership role preferred
Deep understanding of developing strong relationships externally with KOLs, patients, advocacy groups, and payors, etc.
HEOR and field experience are a plus
Consistent record of innovative contributions to medical affairs or development activities which may include high impact publications, regulatory filing, or product launch experience
Experienced with the design and conduct of clinical trials and clinical operations
Excellent communication skills required, including ability to create new materials to be used for both internal and external stakeholders
Strong customer orientation and focus
Ability to create, innovate, and flex to changing environments is essential
The position is in South San Francisco and may require up to 20% time traveling