Denali Therapeutics is dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine.
Denali Therapeutics is seeking to recruit a Director of Nonclinical Safety (Toxicology). The Toxicologist will lead safety strategies for small and large molecule discovery and development programs, and work in close collaboration with colleagues in Research and Development.
Lead the Toxicology group
Function as a project toxicologist in project teams
Design and oversee nonclinical toxicology programs and strategies to advance Denali’s pipeline of small and large molecule therapeutics (non-GLP and GLP studies)
Analyze, interpret, and summarize nonclinical safety data and present data to internal project teams and leadership
Author regulatory documents
Lead investigative efforts into mechanisms of toxicity as needed
Develop and implement target de-risking and screening strategies in discovery teams to support safety lead optimization efforts.
Project Team Leadership
PhD in Toxicology, Biology, Pharmacology or related scientific discipline
12+ years of biotech/pharmaceutical drug discovery/development experience
Expert knowledge of small molecule Toxicology in Drug Development
Strong scientific background and scientific aptitude
Excellent critical thinking and scientific skills
Demonstrated ability to work effectively and collaboratively on cross-functional project teams
Ability to work in a fast-paced environment
Excellent oral, presentation, and written communication skills