Senior Technology Development Scientist

JOB DESCRIPTION
Turn Biotechnologies is currently seeking a qualified, highly motivated individual for the position of Senior Technology Development Scientist.

The employee will be a highly motivated and innovative individual responsible for the scientific/technical aspects of assigned to exploration and development of new mRNA technologies through novel design and synthesis studies. The position work on the cutting edge of this burgeoning field of mRNA-based therapeutics.

COMPANY
Based in Mountain View, California, Turn Biotechnologies, Inc. is a development-stage company focused on restoring cells’ youthful vigor to repair damage caused by the aging process. Using a proprietary ERA™ Platform, we develop mRNA medicines that are specially formulated to instruct specific cells in the body to fight disease or repair damaged tissue. We do this by reprogramming the epigenome to restore cell function that people often lose as they age. This approach can be used to revitalize different cells throughout the body. We are researching its applicability across multiple therapeutic areas, including dermatology, osteocartilage, ophthalmology and muscular indications.

RESPONSIBILITIES:

• Essential duties of the position include:
• mRNA synthesis by in vitro Transcription
• IVT Plasmid design and sequence optimization
• Cloning, expression and purification of DNA and RNA polymerases
• Mammalian cell culture, transfections and cell imaging
• Immunohistochemistry and ELISA assay optimization
• Organize data, maintain detailed records, and communicate results
• Develop, validate, and write technical reports

Additional duties may include:

• qPCR and bioanalyzer evaluation
• Protein quantification assays
• Basic testing in animals
• More advanced quality assessment; HPLC, LCMS, etc.

QUALIFICATIONS
Main

• Background, 7-10 years, in gene design/therapy work
• Background, 5-7 years, in cell culture work and assays
• Problem solving and troubleshooting capabilities
• Autonomous execution capacity with collaboration with other team members
• Excellent verbal and written communication skills
• Track record of safe and meticulous implementation

Auxiliary

• Experience with mRNA therapeutics development
• Work in one or more of the focal application areas: Dermatology, Osteocartilage, Ophthalmology or Muscular
• History with new construct design and implementation

EDUCATION/EXPERIENCE

• PhD in molecular and cellular biology or related discipline preferred
• Alternatively, BS/MS in the same disciplines with 7-to-10 years of relevant research experience in industry
• Google Suite and/or MSOffice skills (Outlook, Word, Excel, PowerPoint, Project)

DESIRABLE CHARACTERISTICS

• Strong work ethic
• Proactive and organized
• Results oriented
• Quick learner
• Troubleshooting and problem-solving capacity
• Goal- and data driven
• Strong interpersonal skills and collaborative mindset

Turn Biotechnologies is an equal opportunity employer and values diversity. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status or disability status.