Formulation Scientist

Loyal is an early stage company developing drugs to help dogs live longer, healthier lives. We apply innovative approaches to tackling aging as a disease that can be slowed and improved with medicines. Loyal is an early stage start-up company and is well funded by top venture capitalists and angels. Loyal is founded and led by a first-gen, female CEO – we encourage and look forward to diverse applicants.

Loyal is looking for an ambitious scientist to assist our CMC & Formulation team. This is an excellent opportunity for a Formulation Scientist to help in building a team from the ground up. Your team will drive all aspects of drug development and manufacturing.

As Part of the CMC Team You Will Be

• • Assisting the planning and execution of drug product development from pre-formulation, formulation development and characterization, production of pre-clinical and clinical trial materials.
  • Developing formulations alongside Contract Development and Manufacturing Organizations (CDMOs).
  • May include overseeing and performing hands-on development experiments for drug product formulations in our in-house lab.
  • Manage collaborations with Contract Development and Manufacturing Organizations (CDMOs)
  • Identification and selection of technically competent CDMOs
  • Negotiation of supply and service agreementsTechnical due diligence of CDMO proposals, protocols, data and reports
  • Strategic and tactical input to the overall product development plans including raw material sourcing, formulation development, quality, and manufacturing aspects.
  • Proactively identifying issues, risks, and opportunities to improve and optimize product development and manufacturing processes
  • Authoring/reviewing CMC sections for regulatory filings and, if requested, interacts with regulatory agencies to answer questions
  • Help in building out the team as needed, this is your chance start from the ground floor and build in your vision

About You

• • You have a Bachelor’s in Chemistry, Chemical Engineering, or related physical science
  • 2+ years of experience in a similar role and demonstrated successful track record of executing drug product development
  • You have experience managing CDMOs or equivalent
  • You have industry expertise in key CMC areas such as various types of API synthesis, formulation development and GMP production, and analytical development.
  • Comfortable with developing multiple types of delivery systems - not just oral

How You Work & Think

• • Adaptability, creativity and high-performer in risk-assessment and strategic thinking
  • You have a track record of operating - as the team grows, you will be helping to design and then execute on your strategy
  • Detailed eye for logistics and problem solving
  • Startup mindset: work fast, low ego, comfortable with uncertainty, and collaborative
  • You are comfortable managing others- laterally, up, and direct reports

The Fundamentality of Health | Good health is critical to every other human (and animal!) experience. We believe health is a fundamental right and are dedicating our lives to maximizing health and developing better medicines for the worst diseases.

Truth Seeking & Feedback Loops | Uniquely in biology, there is a predetermined truth of whether a specific drug will work or not — we just have to catch up with biology! We seek out this truth and do not shy away from inconvenient truths. This holds for personal development too: we are always searching for feedback loops and embody a perpetual growth mindset.

Morality & Empathy | We are developing medicines that may one day be given to a living animal, medicines that if designed badly could hurt that animal instead of help. This is a huge responsibility and should be respected as such. Our work needs to adhere to the strictest moral code and always integrate empathy for the patient.

Transparency | We believe full transparency in thoughts, opinions, intentions, and actions (both good ones and mistakes) is a better way to build a business and work together.

Kindness | Great business(wo)men do not need to be ruthless — you can execute excellently with kindness.

Dog gifs | We love them.