The oncology group is looking for an exceptional candidate to undertake a project focused on studying the biology of ubiquitin-dependent protein degradation. This position presents a unique opportunity to work alongside oncology scientists at the intersection of basic and translational biology. The candidate will also collaborate widely across biological disciplines to gain new and meaningful insights into biological mechanisms. The ideal candidate must demonstrate a record of achievement in their previous field of study, be highly motivated to tackle complex questions in basic biology and have the ability to work both independently and in close collaboration with other groups.
PhD in cell and molecular biology, biochemistry, or a related discipline
Experience with a wide variety of techniques that pertain to mammalian cell culture and molecular biology, and a strong desire to master new techniques and data analysis methods when necessary
Scientific drive to pursue a mechanistic understanding of fundamental biological processes
A strong record of productivity, creativity and independent thought evidenced by previous work and publications
Nice to haves:
Experience with cell line generation (overexpression, knock-in, knock-out, gene silencing)
Experience with genetic screening approaches using Crispr/Cas9
An understanding of ubiquitin biology
Calico Postdoctoral Fellowship Program:
Calico’s Postdoctoral Fellowship Program pairs recent PhD graduates with internal expertise to conduct fundamental and innovative research and investigate meaningful scientific questions aligned with our mission to understand the biology of human aging and develop interventions for age-related diseases. Postdoctoral Fellows at Calico receive mentorship and support to develop independent research programs to enable the next stage of their careers. In addition to direct mentorship from their host laboratories, Postdoctoral Fellows benefit from collaboration with diverse scientists across Calico’s Research and Technology groups and are encouraged and supported to communicate their findings through high-impact, peer-reviewed scientific journals and conferences.
Fully integrated into Calico’s labs and community, Postdoctoral Fellows pursue new research directions with devoted resources for innovative and potentially high-risk research and bring new personalities, ideas, technology and perspectives to Calico.
Calico’s program is a fixed-term educational assignment for individuals who have recently completed their PhD degrees, have had a meaningful first author paper accepted for publication, and have made important contributions to science in their area.
While postdocs will focus on their own project(s), mutually agreed to in principle and prior to making the decision to join the mentor’s lab, the expectation is that they all contribute to furthering our understanding of aging and age-related diseases.
Postdoc assignments are up to four years in length. It is expected that the postdoc will receive regular feedback and guidance from their mentor in addition to participating in a more formal annual review process to discuss project progress, individual performance, and career coaching.
Our postdoc projects are expected to yield work that can be submitted for publication in a timely fashion upon completion and are intended to train people to become independent investigators in an academic or industry setting upon successful completion of the assignment.
Calico postdocs join a community of other Postdoctoral Fellows who regularly engage with members of Calico’s scientific community, including senior leadership, through a variety of professional and career development opportunities.