Biostatistician (Pre-Clinical Research)
- Alkahest
- Full time
- San Carlos, California
- Posted: August 5, 2020
Company
Description
Uniquely positioned to enhance quality of life in aging, at Alkahest, we are pioneering science that is rapidly being translated to the clinic. Our approaches utilize in vivo,in vitro, proteomic, and molecular techniques to identify new therapeutics and apply them to patients.
We are seeking a highly motivated Biostatistician. The role will be to lead, advise and assist in the data analysis aspects of the setup, evaluation, and interpretation of large scale proteomics/biomarker studies and other biological studies in a clinical and pre-clinical capacity.
These studies will involve cutting edge science and the efforts of this role will be pivotal in advancing our therapeutic capabilities.
The role requires dedication, flexibility, excellent communication and organization to successfully drive the science and achieve Alkahest’s corporate mission.
Responsibilities:
- Serve as the clinical biostatistics lead for Alkahest and provide advice and mentorship as needed
- Aid in the experimental design of clinical studies to ensure an informed choice is made when balancing resource allocation and result expectations
- Define and perform the statistical analyses of exploratory endpoints in Alkahest’s clinical studies
- Identify and develop cutting edge statistical techniques to analyze large scale proteomics and other omics datasets
- Assist Alkahest clinical and research teams in the interpretation of analyzed data
- Closely work with pre-clinical biostatistics to ensure seamless translation of methodology
- Develop predictive capabilities for Alkahest’s scientific areas of focus, using the appropriate statistical and machine learning methodologies
- Ensure completeness, correctness and integrity of analyses and datasets
- Engage external resources to apply cutting edge methodologies and ensure recognition in the scientific community including publications
- Other responsibilities as assigned.
Requirements:
- PhD. in Statistics, Biostatistics, or related field
- Significant experience (4+ years) working with clinical study data and developing statistical analysis plans.
- Strong experience with multiple types of large scale omics data (RNAseq, proteomics)
- Solid expertise in statistics and modeling, including but not limited to linear and non-linear modeling, multivariate analysis, network analysis, machine learning, and algorithm development
- Strong statistical programming skills in SAS and R
- Programming/scripting experience in languages such as Python or Perl is a plus
- Experience supporting neuroscience or aging research a plus
- Creative problem solving with the ability to think outside-of-the-box
- Strong team spirit but also the ability to self-motivate and work independently
- Excellent interpersonal, verbal and written communication skills
- Attention to detail and strong organizational skills
- Comfortable working in a multi-tasked, fast-paced startup environment
Apply today. We'd love to meet you!