Research Associate II, Immunology

Who is BlueRock?

BlueRock Therapeutics, a wholly-owned and independently operated subsidiary of Bayer AG, is a leading engineered cell therapy company using its unique CELL+GENE™ platform to direct cellular differentiation and genetically engineer cells to create a new generation of cellular medicines that address large patient populations suffering from neurological, cardiovascular, and immunology diseases.

The convergence of cell biology and genetic engineering is creating fundamental new ways to impact disease. Founded in 2016 to capitalize on these technological breakthroughs, we are advancing our novel CELL+GENE™ platform to develop, manufacture, and deliver an entirely new generation of authentic and engineered cell therapies across three therapeutic areas: neurology, cardiology, and immunology.

What Are We Doing?

Our foundational science harnesses the ability to create and then direct the differentiation of universal pluripotent stem cells into authentic, functional cells that can be used as allogeneic cellular therapies to treat a broad array of diseases. We can also further engineer these cells, enabling them to produce enzymes, antibodies, and other proteins for additional therapeutic benefit.

We are passionate about delivering on the promise of cellular and gene therapy, shaping the future of cellular medicine, and delivering new therapies to millions of patients with treatment options.

We are seeking individuals who are collaborative, thrive in a fun and dynamic culture, and are steadfast in the commitment to advance cutting-edge cellular therapies to impact patients’ lives.

Description of Position:

BlueRock Therapeutics is seeking a highly motivated individual to join our Immunology team in Cambridge, MA. The successful candidate will have hands on experience in Immunology and immune cell biology. This individual will join a team of scientists to engineer novel immune cell therapies derived from induced Pluripotent Stem Cells (iPSC) for the treatment of inflammatory or autoimmune diseases. This is an exciting and challenging opportunity to contribute to bringing a new class of cellular therapies to patients with seriously debilitating diseases using our unique CELL+GENE platform.

Responsibilities:

• Work closely with scientists to perform experiments for proof of concept studies in vitro and in vivo
• Isolate and culture primary and engineered human immune cells
• Characterize immune cells by multicolor flow cytometry and assess their functions using cell-based assays
• Generate and collect data, and communicate the results effectively to peers
• Document experimental data in electronic laboratory notebooks in a timely and accurate manner in accordance with the company quality management system
• Collaborate with other team members as needed to advance our immunology programs
• Attend and present data at laboratory team meetings

Minimum Requirements:

• Minimum of a Bachelor’s or Master’s degree in Immunology or related discipline is required
• Minimum of 2 years of relevant experience in discovery research settings is required
• Hands on experience with mammalian cell culture such as primary immune cells is required
• Experience with multi-color flow cytometry and cell-based functional assays, including cell proliferation, cytokine and cytotoxicity assays is required
• Self-motivated; highly organized work style; ability to maintain detailed documentation
• Ability to work effectively with peers in a results-oriented research environment
• Effective communication and interpersonal skills

Working Environment:

• In this position you will work in a controlled laboratory environment
• You may be periodically required to move heavy equipment up to 50lbs
• There is a risk of potential exposure to chemicals and biohazards
• Working in the laboratory requires mandatory use of personal protective equipment

Equal Opportunity Workplace: At BlueRock, we welcome and support differences and diversity and we are proud to be an equal opportunity workplace. Please let us know if you require disability-related accommodation or other grounds protected by human rights legislation during the recruitment process so that we can work with you to meet your needs.