Associate Director/Director of In Vivo Biology/Pharmacology

About BioAge

BioAge Labs is a clinical-stage venture-backed biotechnology company headquartered in Richmond, CA. We’ve built a systems biology platform to map out the key molecular pathways that impact healthy human aging, based on proprietary human aging cohorts that have blood samples collected up to 45 years ago with participant -omics data that is tied to detailed medical follow-up records over their lifespan. To date, BioAge has raised $127M from Andreessen Horowitz, Kaiser Foundation Hospitals, and others. Recently, BioAge in-licensed our first two platform assets, and for both programs we’ll be initiating Phase 2 efficacy trials by H1 2021. Our mission is to develop a pipeline of therapeutic assets that increase healthspan and lifespan. For additional information about BioAge, visit the company’s website atwww.bioagelabs.com.

About the position

We are seeking an accomplished, energetic, and detail-oriented leader to join our team as an Associate Director/Director of In Vivo Biology/Pharmacology to push forward our drug discovery efforts. The qualified candidate is a highly motivated, interactive, and team-oriented individual that possesses the ability to work across a highly matrixed environment to provide technical and scientific in vivo expertise to advance drug discovery programs from target identification/validation to IND-enabling activities.

This is a new position at BioAge, and a key role to drive novel target validation and development, as well as provide preclinical support for our clinical-stage programs. The Associate Director/Director of In Vivo Pharmacology will lead and mentor a small group of scientists and technicians responsible for developing and executing our internal in vivo experiments, as well as help manage key relationships and develop detailed experimental plans with an array of external CROs. The candidate will be part of the preclinical leadership team. This is a unique opportunity to be part of a rapidly growing company developing a pipeline of therapies with the potential to enhance healthspan and lifespan in an aging population.

Responsibilities

• Leading, managing, and mentoring the internal in vivo team, including vivarium staff
• Managing BioAge’s internal preclinical aging and frailty validation platform
• Developing detailed experimental plans for preclinical CROs as well as for internal investigation
• Developing high quality and reproducible animal models for efficacy and mechanism of action studies of small molecule and biologic therapeutics, in close collaboration with therapeutic area teams, pharmacology, medicinal chemistry, preclinical safety, DMPK, etc
• Assisting with the evaluation, optimization, and management of preclinical CROs
• Oversight of vivarium management and membership in the Institutional Animal Care and Use Committee
• Contribution to preclinical strategy, vision, and operation

Qualifications, Skills, & Abilities

• DVM or PhD with at least 10 years of drug discovery experience, and at least 3 years in a group leadership and management role.
• At least 5 years experience in a small biotech/biotech startup environment strongly preferred
• Very strong understanding of development of animal models and general physiology in a drug discovery setting
• Enthusiastic mentor and leader with experience managing research scientists
• Highly organized and detail oriented with experience developing and executing on project plans and timelines, as well as budget management
• Extensive experience drafting detailed experimental plans and managing preclinical CROs
• Excellent communicator with exceptional verbal, presentation, and written communication skills
• Excellent working ability across a highly matrixed environment
• Some expertise in aging/and/or age related diseases/disorders in animal models preferred

BioAge offers a comprehensive compensation package, as well as generous paid time off in addition to company-observed holidays. We provide medical, dental, and vision insurance, along with a 401(k) retirement savings plan which includes matching employer contributions. We also pride ourselves in giving employees many opportunities for career development including a generous annual budget for continued learning, a direct and open-door environment, and a dedication to training and skill development.

BioAge is an equal opportunity employer. In accordance with anti-discrimination law, it is the purpose of this policy to effectuate these principles and mandates. BioAge prohibits discrimination and harassment of any type and affords equal employment opportunities to employees and applicants without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. BioAge conforms to the spirit as well as to the letter of all applicable laws and regulations.