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    Director, In Vitro Pharmacology

    • Altos Labs
    • Full time
    • San Francisco, California
    • Posted: November 24, 2023
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    Company
    Altos Labs

    Our Mission

    To restore cell health and resilience through cellular rejuvenation programming to reverse disease, injury, and the disabilities that can occur throughout life.

    For more information, see our website at altoslabs.com.

    Diversity at Altos

    We believe that diverse perspectives are foundational to scientific innovation and inquiry.

    We are building a company where exceptional scientists and industry leaders from around the world work side by side to advance a shared mission.

    Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives.

    At Altos, we are all accountable for sustaining a diverse and inclusive environment.

    What You Will Contribute To Altos

    As a Director of In Vitro Pharmacology in the Institute of Medicine (IOM) at Altos Labs, you will join a dynamic team in a unique environment where leading research labs work side by side with industry scientists. You will be responsible for building and leading a team to develop biophysical, biochemical and cell-based assays. Your work will support our efforts to understand the deep mechanistic biology of rejuvenation/aging in support of target validation. Additionally, you will contribute to our drug discovery campaigns through the selection of drug candidates and support a diverse portfolio of early exploratory and drug-discovery stage projects. Your expertise and leadership will be instrumental in driving our mission forward and making a significant impact in the field of aging/rejuvenation biology and drug discovery.

    Responsibilities

    • Build, lead and mentor a team to develop and optimize cellular and biochemical assays to support our understanding of the deep mechanistic biology of rejuvenation/aging.
    • Implement in vitro pharmacology strategies to validate targets and elucidate mechanisms of action for potential drug candidates.
    • Collaborate with Institute of Science (IOS) labs and cross-functional teams to identify and validate novel drug targets.
    • Work closely with process development and analytical development teams in Technical Operations to discover processes and assays that will align with their downstream operations.
    • Provide scientific leadership and expertise in the field of aging/rejuvenation biology.
    • Drive data analysis and interpretation to guide decision-making processes.
    • Support a diverse portfolio of early exploratory and drug-discovery stage projects.
    • Stay abreast of the latest scientific and technological advancements in the field.

    Who You Are 

    Qualifications

    • PhD in Pharmacology, Biology, Biochemistry, or a related field and a minimum of 10 years of industry experience in leading in vitro research in a drug discovery and development setting.
    • Extensive experience in cellular and biochemical assay development.
    • Proven track record of solving complex biological mechanisms.
    • Demonstrated ability to lead and influence cross-functional teams.
    • Excellent communication and presentation skills.

    Preferred Qualifications

    • Experience working across diverse therapeutic modalities, including small molecules, biotherapeutics, nucleic acid therapeutics, and gene therapy is highly desirable.
    • Experience working on cellular models of diverse age-related conditions is desirable, including metabolic, musculoskeletal, immune-related as well as cardiovascular and neurodegenerative diseases.
    • Strong experience in the field of aging/rejuvenation biology.

    The salary for the Director level is: $260,950 - $353,050. Exact compensation may vary based on skills, experience, and location.

    • Biology
    • Chemistry
    • Clinical Development
    • Management

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