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    Group Leader, Antibody Development

    • Calico
    • Full time
    • San Francisco, California
    • Posted: February 21, 2022
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    Company
    Calico

    We are seeking a highly motivated individual to lead an antibody development team focused on large scale data generation and validation. The candidate will take on a leadership role and establish an antibody development group that will develop novel display and protein interaction technologies. The candidate will interact with a multidisciplinary team consisting of computational scientists, machine learning engineers, structural biologists, biochemists, and antibody engineers.

    Role: 

    • Build a state-of-the-art display and protein-protein interaction group utilizing known (phage, yeast, mRNA, ribosomal, mammalian) and novel display and protein-protein interaction technologies to enable high throughput interaction identification.
    • Be a thought leader for our rational antibody design team
    • Work collaboratively and cross functionally across multiple teams

    Requirements:

    • PhD in biochemistry, structural biology, immunology, molecular biology, or related field and at least 10 years of experience.
    • Deep expertise in display, directed evolution and other in vitro targeting technologies.
    • Expertise in antibody structure, design, and engineering.
    • Knowledge of antibody library design and architectures.
    • Knowledge of machine learning technologies as applied to protein structure
    • Proven track record of scientific accomplishment in the field of antibody development and design as evidenced by publication record or industry achievements.
    • Management
    • Clinical Development
    • Biology
    • Immunology

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