Calico is seeking a highly motivated and experienced pathologist to establish, manage and lead a histopathology core within the in vivo sciences group. This position offers the exciting opportunity to provide research direction and advance state-of-the-art in a new initiative supporting Calico’s translational medicine effort, with a focus on aging and age-related diseases. The successful candidate will have single point of contact responsibility for Calico’s research pathology, both in-house and external collaborations, and will be expected to oversee pre-clinical pathology studies as programs advance into clinical drug development. The core is expected to provide both routine and cutting-edge histopathology services and expertise to Calico scientists and the lead will be responsible for acquiring instrumentation, technical personnel and new technologies to run the core facility. The Pathologist is expected to define our long-range strategy in support of our experimental medicine initiatives, develop innovative image analysis techniques (including machine learning) in collaboration with several technology labs., and automation to enable digital pathology. Calico provides a scientifically stimulating and collaborative working environment and promotes a culture of data-driven scientific investigation and publication. This position will report to the Head of In Vivo Sciences.
Establish a modern pathology core at Calico. Organize the hiring and supervision of additional pathologists for the pathology core when the need arises.
Directly interface with Calico scientific personnel who are engaged in discovery/development to advise them on appropriate histopathology endpoints and modalities that will best inform program decisions and directions, ideal site for specific studies (in-house v/s CROs) and data interpretation and auditing.
Provide Calico with expertise concerning human tissue procurement and banking including advise on commercial vendors, pharma and academic entities that are best suited to the specific needs of a given project.
Actively identify and implement new technologies relevant to histopathology by staying current with these technologies and working closely with internal partners or external entities as appropriate to Calico’s business needs.
D.V.M. and Ph.D. or the equivalent degree, post-doctoral training and at least 3 years of independent experience in a research environment in academia or the pharmaceutical industry (as evidenced by publications, patents, IND filings etc.)
Board certification by the American Board of Pathology (for MDs) or by the American College of Veterinary Pathology (for DVMs) is highly desirable
Previous experience with computational approaches to digital pathology is required
Strong interpersonal and leadership skills, excellent ability to communicate with a diverse range of “clients” and experience managing one or more technical staff