Senior Scientist - Ophthalmology

Turn Biotechnologies is currently seeking a highly qualified scientist for the position of Senior Scientist - Ophthalmology.

The employee will be a highly motivated and innovative individual responsible for the scientific/ technical aspects of evaluating novel mRNA-based therapeutics for epigenetic reprogramming and rejuvenation of ocular tissue for the treatment of age-related ophthalmic indications. This lab-based position will be critical to the development, evaluation, and application of Turn’s cutting-edge technology for its ophthalmology pipeline.

Responsibilities

• Design and perform experiments using established and novel ophthalmic models to evaluate epigenic reprogramming in various eye cell populations and tissues
• Evaluate drug delivery, transfection efficiency, and therapeutic efficacy of Turn’s platform technology in ophthalmic in vitro, ex vivo, and in vivo models
• Establish and maintain cell and tissue culture model systems
• Assist in the mentoring of research assistants and/or laboratory technicians
• Proficient execution of standard molecular and cell biology techniques including cloning (plasmid construction, mutagenesis), RNA/DNA manipulation (DNA sequencing, enzyme digestion/modification, agarose gel electrophoresis, PCR, RT-PCR), protein analysis (ELISA, Immunoprecipitation, SDS-PAGE and Western blotting), transfection, ddPCR, routine mammalian cell culture, cell transfection, and various types of microscopy for cell and tissue imaging
• Develop, validate, and write laboratory protocols and technical reports
• Organize data, maintain detailed records, and effectively communicate results in a timely fashion

Qualifications

Education/Experience:

• PhD, MD, or MD/PhD in cellular biology, biochemistry, molecular biology, or related discipline; candidates with relevant industry experience will also be considered
• Background including developmental and stem cell biology is a significant plus
• 5-7 years’ experience (beyond Ph.D., including post-doctoral work) in ophthalmology-related translational research
• Industry experience is a significant plus
• Experience in cell and tissue culturing and assays specific to eye-related research
• Experience using animal and ex vivo tissue models of ocular indications
• Experience in ophthalmic drug development, delivery and evaluation is a significant plus
• Experience in genetic engineering, flow cytometry, confocal microscopy, RNAseq/ChIPseq, advanced molecular biology, genomic data analysis, and/or other cutting-edge analytical methods is highly desirable
• Collaboration with other teams and team member across company programs
• Exceptional written and oral communication skills

Auxiliary:

• In addition to ophthalmology, experience in one or more of focus areas (dermatology, immunology, and oncology) will be a plus
• Experience developing and evaluating mRNA-based, gene editing, or ophthalmic therapeutics
• Novel animal model system adaptation and application

Required Characteristics

• Ownership mindset
• Ability to excel in a fast-paced biotechnology environment and achieve goals and milestones with quality, precision, and speed
• Ability to solve complex problems creatively, whether scientific or managerial in nature.
• Ability to work independently, show self-initiative and attention to detail, and motivation to explore new techniques and concepts are essential
• Strong work ethic
• Proactive and organized
• Superior interpersonal skills

Why Choose Turn Bio?

We are a close-knit, collaborative team, passionate about anti-aging and longevity and it's impact and improvement of age-related disease and the quality of people’s lives

• Competitive compensation
• Benefits Package
• Fully-paid employee medical, dental, vision, & life insurance)
• 401K
• FSA
• Flexible PTO
• Employee Assistance Program

You will be a vital part of the company and have tremendous impact on its success

Equal Opportunity Employer Statement: Turn Biotechnologies is an Equal Opportunity Employer that values and respects the importance of a diverse and inclusive workforce. We do not discriminate on the bases of race, color, religion, sex, age, national origin, veteran status, disability, genetic information, pregnancy, sexual orientation, or gender identity. We recognize that diversity and inclusion is a driving force in the success of our company.

Occupational Health and Safety: Turn Biotechnologies provides a workplace free from recognized hazards and complies with standards, rules and regulations issued under the OSH Act.