Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico’s highly innovative technology labs, its commitment to curiosity-driven discovery science and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.
Calico is seeking an exceptional Project Team Leader (PTL) to partner with key stakeholders to define the vision and drug discovery and development strategy for assigned programs, and to provide experienced leadership and direction to the cross-functional team.
The successful candidate will
Lead the project team for pipeline compounds as they transition from candidate nomination through IND filing and early development through clinical Proof of Concept.
Be responsible for partnering with key stakeholders in developing and/or refining the strategic overview (vision, strategic context, and core strategy) for assigned programs.
Be accountable for presenting strategic overview to Calico’s Drug Development Review Committee (DDRC) for endorsement
Be responsible for ensuring cross-functional matrix decisions are made in a timely manner and are aligned with DDRC endorsed strategic overview for the program.
Ensure strategic plans and decisions are considered and evaluated, weighing speed, cost, and probability of technical and regulatory success. Present options and recommendations for assigned programs at key inflection points to the DDRC for final decision.
Ensure assigned programs are appropriately resourced and in accordance with specified timelines and budgets
Ensure the team achieves and maintains a successful team dynamic with a high-level of sustainable performance. In particular, the PTL must ensure the opinions and perspectives of internal and external partners and stakeholders are heard and understood.
As deemed appropriate, contribute to the establishment and improvement of processes to support the drug discovery and development portfolio
A PhD degree in life sciences or a scientific discipline related to drug development and/or an MD/PharmD is preferred
At least 10 years of biotech/pharmaceutical industry experience in drug development, preferably in both non-clinical and early clinical drug development
Excellent knowledge of drug development processes and deliverables at each stage of the pipeline
Successful track record of leading projects/program teams in a cross-functional team environment from pre-IND-enabling activities through early clinical development (ideally through NDA filing)
Experience successfully leading projects with participation by external collaborators
Excellent leadership skills with exceptional decision-making and analytical skills
Strong interpersonal and communication skills as well as proven ability to build and maintain positive working relationships, promote collaborations, and to lead through the ambiguity of developing novel therapeutics in unchartered territory
Must be willing to work onsite three days a week
Calico requires all new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Calico will consider requests for Reasonable Accommodations.