Company Summary
Juvena Therapeutics is on a mission to discover and develop biologics for rare and chronic degenerative diseases by mining the secretomes of human pluripotent stem cells through a machine learning (ML)-enhanced platform. Juvena’s approach integrates proteomics, transcriptomics and imaging with phenotypic human in vitro disease model screening and extensive preclinical validation to mine stem cell secretomes as a rich source of new medicines for chronic and rare diseases. We are advancing leads for muscular dystrophies and muscle atrophy, and validating hits across metabolic and pulmonary diseases with a goal to identify and develop two new assets in new disease indications over the next two years. Since our launch in mid-2018, Juvena has discovered dozens of hits for neuromuscular, skeletal, metabolic and pulmonary diseases, including several muscle regenerative protein therapeutic candidates with potent human in vitro and mice in vivo efficacy. Juvena is advancing a developmental candidate for Myotonic Dystrophy Type 1, a rare autosomal dominant, progressive muscle-wasting disease, in IND-enabling studies.
Juvena Therapeutics has secured venture capital, NIH, and CIRM funding to develop our top lead to a clinical-stage investigational new drug, to build our stem cell secretome database, and to leverage our discovery platform to rapidly identify and validate novel protein-based drug candidates for multiple rare and chronic diseases across metabolic and pulmonary therapeutic areas. At Juvena we embrace a diversity of backgrounds, experience and approaches that all combine to lead us to world-class scientific results in an inclusive environment.
Apply to this Job through the following means:
Please email your CV and Cover Letter to apply@juvenatherapeutics.com with the title of the position as the subject line.